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Stud Mycol 59(1): 39-46 2007
DOI: 10.3114/sim.2007.59.05
Copyright © 2007 CBS Fungal Biodiversity Centre
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Aspergillus species identification in the clinical setting

S.A. Balajee1,*, J. Houbraken2, P.E. Verweij3, S-B. Hong4, T. Yaghuchi5, J. Varga2,6 and R.A. Samson2

1 Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, U.S.A.
2 CBS Fungal Biodiversity Centre, Utrecht, The Netherlands
3 Department of Medical Microbiology, Radboud University Nijmegen Medical Center and Nijmegen University Center for Infectious Diseases, Nijmegen, The Netherlands
4 Korean Agricultural Culture Collection, Suwon, Korea
5 Medical Mycology Research Center, Chiba University, Chiba, Japan
6 Department of Microbiology, Faculty of Sciences, University of Szeged, H-6701 Szeged, P.O. Box 533, Hungary

* Correspondence: S. Arunmozhi Balajee, fir3{at}cdc.gov

Multiple recent studies have demonstrated the limited utility of morphological methods used singly for species identification of clinically relevant aspergilli. It is being increasingly recognised that comparative sequence based methods used in conjunction with traditional phenotype based methods can offer better resolution of species within this genus. Recognising the growing role of molecular methods in species recognition, the recently convened international working group meeting entitled "Aspergillus Systematics in the Genomic Era" has proposed several recommendations that will be useful in such endeavors. Specific recommendations of this working group include the use of the ITS regions for inter section level identification and the β-tubulin locus for identification of individual species within the various Aspergillus sections.

Keywords Emericella / molecular phylogeny / pathogenic aspergilli / polyphasic taxonomy / section Aspergillus section Terrei / section Usti




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